Table 4.
HRV frequency–domain parameters by OSA status in a cohort with atrial fibrillation
| All patients | No OSA AHI < 5/h | OSA AHI > 5/h | p value | p value (adjusted for age, sex, BMI) | |
|---|---|---|---|---|---|
| n = 89 | n = 35 | n = 54 | |||
| †High frequency (ms2) | |||||
| Non-REM | 333.3 (437.8) | 238.8 (913.9) | 403.5 (723.7) | 0.643 | 0.730 |
| REM | 223.3 (437.8) | 206.6 (344.1) | 239.8 (531.1) | 0.530 | 0.426 |
| High frequency–normalised units (%) | |||||
| Non-REM | 44.5 ± 15.6 | 39.1 ± 15.7 | 48.0 ± 14.6 | 0.008 | 0.024 |
| REM | 37.4 ± 17.2 | 32.6 ± 16.0 | 40.5 ± 17.4 | 0.036 | 0.143 |
| †Low frequency (ms2) | |||||
| Non-REM | 336.1 (863.9) | 339.6 (1155.7) | 327.6 (760.1) | 0.447 | 0.559 |
| REM | 302.9 (817.5) | 358.5 (1103.7) | 298.8 (831.0) | 0.533 | 0.904 |
| Low frequency–normalised units (%) | |||||
| Non-REM | 47.8 ± 19.2 | 54.1 ± 19.7 | 43.7 ± 18.0 | 0.012 | 0.045 |
| REM | 55.2 ± 22.1 | 60.4 ± 20.8 | 51.8 ± 22.5 | 0.076 | 0.228 |
| †Very low frequency (ms2) | |||||
| Non-REM | 470.0 (860.0) | 603.8 (1055.1) | 445.2 (605.6) | 0.135 | 0.148 |
| REM | 865.4 (1322.0) | 954.9 (1548.9) | 826.5 (1307.6) | 0.417 | 0.663 |
| LF/HF ratio (nu) | |||||
| Non-REM | 1.5 ± 1.5 | 2.1 ± 2.0 | 1.2 ± 1.0 | 0.007 | 0.018 |
| REM | 2.3 ± 2.2 | 2.9 ± 2.6 | 2.0 ± 1.9 | 0.063 | 0.108 |
| †Total power | |||||
| Non-REM | 1352.7 (2078.9) | 1183.2 (1514.3) | 1109.0 (1573.3) | 0.526 | 0.987 |
| REM | 1128.2 (1498.7) | 1439.0 (2360.6) | 1318.0 (2137.8) | 0.666 | 0.988 |
Data are presented as mean (SD) or median (IQR). Natural log-transformed data are indicated by †. High frequency: power in the 0.15–0.40 Hz band; high frequency–normalised units: HF power divided by power ≥ 0.04 Hz; low frequency: power in the 0.04–0.15 Hz band; low frequency–normalised units: LF power divided by power ≥ 0.04 Hz; very low frequency: power less than 0.04 Hz; LF/HF, low frequency/high frequency ratio: low frequency power divided by high frequency power; total power: power from 0 to Nyquist frequency