Table 2.
Final selection of PROMs
| PRO(s) | Generic PROM(s) | # items | ||
|---|---|---|---|---|
| Overarching | Quality of life | PROMIS® Global02 | 1 | |
| TOPICS-SF NRS Quality of life* | 1 | |||
| EORTC QLQ-c30-v3 Quality of life (item 30)** | 1 | |||
| Perceived health | PROMIS® Global01 / SF-36—question 1 | 1 | ||
| TOPICS-SF NRS Overall health* | 1 | |||
| EORTC QLQ-c30 v3 Perceived health (item 29)** | 1 | |||
| Functioning | Participation in social roles | PROMIS® Ability to Participate in Social Roles and Activities [4a / 6a / 8a / CAT]*** | 4–12 | |
| SF-36/RAND-36 Role Functioning (emotional and physical problems) | 7 (3 + 4) | |||
| Utrecht Scale for Evaluation of Rehabilitation-Participation (USER-Participation)v | 11 | |||
| Physical functioning | PROMIS® Physical Function [8b / 10a / 10b / 20a / CAT] | 4–20 | ||
| SF-36/RAND-36 Physical Functioning | 7 (3 + 4) | |||
| TOPICS-SF Tasks and activities of daily living* | 10 | |||
| EORTC-QLCc30 v3 Physical Functioning** | 5 | |||
| Mental functioning | Anxiety | PROMIS® Anxiety 4a / 6a / 8a / 7a/ CAT]*** | 4–12 | |
| Generalized Anxiety Disorder -7 (GAD-7) | 7 | |||
| Four Dimensional Symptom Questionnaire (4DKL)—Anxiety | 12 | |||
| Hospital Anxiety and Depression Scale (HADS)—Anxiety | 7 | |||
| Depression | PROMIS® Depression 4a / 6a / 8a / 8b / CAT*** | 4–12 | ||
| Center for Epidemiologic Studies Depression (CES-D) | 20 | |||
| Patient Health Questionnaire (PHQ) [2 / 9] | 2 or 9 | |||
| Four Dimensional Symptom Questionnaire (4DKL)—Depression | 6 | |||
| Symptoms | Fatigue | PROMIS® Fatigue 4a / 6a / 8a / CAT*** | 4–12 | |
| EORTC-QLQ-c30 v3 Fatigue** | 3 | |||
| Numeric Rating Scale Fatigue (NRS-Fatigue) | 1 | |||
| Pain | Numeric Rating Scale Pain Intensity (NRS-Pain intensity) | 1 | ||
| SF-36/RAND-36 Bodily Pain | 2 | |||
Preferred PROMs for each PRO are highlighted in bold
PROMs highlighted in bold constitute the set of PROMs preferred by the working group
*For frail elderly
**For cancer patients without co-morbidities
***When using PROMIS-measuring instruments one can choose from a number of short-forms or CATS with a varying number of questions
****Both scales of SF-36/RAND-36 are needed to measure the PRO-construct Participation in social roles