Table 3.

Histopathological score of kidney tissue.

Group	dose	Healthy rats	5/6 nephrectomy rats
iopamiron	normal	1.9 ± 0.13	1.9 ± 0.44
	high	2.7 ± 0.13	3.0 ± 0.24*
IPL	Normal	–	2.0 ± 0.19
	high	–	2.2 ± 0.34
Control		1.8 ± 0.17	–

*: p < 0.05.

Data are presented as the mean ± standard deviation (SD). The histopathological score of kidney tissue was significantly higher in the NxH groups compared with the sham control group and RN group (p = 0.016, p = 0.032, respectively). There was no significant difference in score between the NxHL and sham control groups or RN group.

IPL: iomeprol-containing liposome, RN: healthy rats with normal-dose iopamiron, RH: healthy rats with high-dose iopamiron, NxN: 5/6 nephrectomized rats with normal-dose iopamiron, NxH: 5/6 nephrectomized rats with high-dose iopamiron, NxNL: 5/6 nephrectomized with normal-dose IPL, NxHL: 5/6 nephrectomized with high-dose IPL.