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. 2023 Apr 14;62:102699. doi: 10.1016/j.redox.2023.102699

Fig. 2.

Fig. 2

Metabolic differences in colon cancer revealed by untargeted metabolome profiling. Sparse partial least-squares discriminant analysis (sPLS-DA) scores plot showing variance of metabolic features between normal colon tissues, KRAS mutant CRCs and KRAS wild-type CRCs. (A) Tumors and normal colon tissues from male patients: KRAS mutant CRCs (n = 27), KRAS wild type CRCs (n = 58), normal colon tissues (n = 27); R2X (0.403), R2Y (0.98), Q2 (0.638), (B) Tumors and normal colon tissues from female patients: KRAS mutant CRCs (n = 35), KRAS wild type CRCs (n = 43), normal colon tissues (n = 12); R2X (0.432), R2Y (0.987), Q2 (0.753).