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. 2023 Apr 25;9(5):e15700. doi: 10.1016/j.heliyon.2023.e15700

Fig. 3.

Fig. 3

Multiple aspects of the contribution of dyslipidemia in the OA process. Dyslipidemia is characterized by high levels of LDL, TAG, FFA and ROS, and low levels of HDL. All these factors contribute to OA development and progression via several mechanisms. FFA: free fatty acids, HDL: high-density lipoprotein, HFD: high-fat diet, LDL: low-density lipoprotein, MMP: matrix metalloproteinases, Ox-LDL: oxidized low-density lipoprotein, ROS: reactive oxygen species, and TAG: triglycerides. Created by Biorender.com.