Table 1.
Summary of patient characteristics
| Variable | Non-progressor | Progressor | p value |
|---|---|---|---|
| N = 70 | N = 35 | ||
| Age [years] | 52.5 [38.2;65.8] | 65.0 [52.0;77.5] | 0.007 |
| Sex at birth | 0.332 | ||
| Female | 32 (46.4%) | 12 (34.3%) | |
| Male | 37 (53.6%) | 23 (65.7%) | |
| BMI [kg/m2] | 25.4 [22.4;29.3] | 28.7 [24.7;31.2] | 0.064 |
| Smoker status | 0.519 | ||
| Current | 6 (16.2%) | 2 (13.3%) | |
| Former | 7 (18.9%) | 5 (33.3%) | |
| Never | 24 (64.9%) | 8 (53.3%) | |
| Solid tumors | 1.0 | ||
| Localized | 6 (8.82%) | 3 (8.57%) | |
| Metastatic | 1 (1.47%) | 0 (0.00%) | |
| Hematologic malignancy | 1 (1.47%) | 3 (8.57%) | 0.113 |
| Arterial hypertension | 20 (31.2%) | 12 (34.3%) | 0.933 |
| Rheumatic disease | 2 (2.99%) | 1 (2.86%) | 1.0 |
| Acute kidney injury | 4 (6.35%) | 3 (9.09%) | 0.689 |
| GCS | 15.0 [15.0;15.0] | 15.0 [15.0;15.0] | 0.461 |
| Blood pressure, systolic [mmHg] | 130 [120;142] | 133 [121;146] | 0.869 |
| Pulse frequency 1/min | 84.5 [75.0;95.0] | 81.0 [76.0;87.8] | 0.488 |
| Temperature [°C] | 37.3 [36.7;38.0] | 37.9 [37.0;38.8] | 0.146 |
| SpO2 [%] | 96.0 [95.0;98.0] | 94.0 [93.0;95.0] | < 0.001 |
| Respiratory rate [1/min] | 16.0 [14.0;18.0] | 18.0 [16.0;19.0] | 0.067 |
| Dyspnea | 15 (22.4%) | 16 (47.1%) | 0.021 |
| Headache | 11 (15.9%) | 7 (20.6%) | 0.758 |
| Diarrhea | 3 (4.41%) | 5 (15.2%) | 0.109 |
| Hemoptysis | 1 (1.49%) | 1 (3.12%) | 0.544 |
| Unconsciousness | 2 (3.03%) | 0 (0.00%) | 0.551 |
| Cough | 29 (42.6%) | 17 (50.0%) | 0.622 |
| Nausea | 10 (14.9%) | 8 (25.0%) | 0.349 |
| ALT [U/l] | 30.0 [20.0;46.5] | 25.0 [19.0;40.5] | 0.793 |
| AST [U/l] | 34.0 [24.8;55.5] | 35.0 [29.5;49.5] | 0.407 |
| Bilirubin (direct) [mg/dl] | 0.30 [0.20;0.45] | 0.40 [0.27;0.58] | 0.498 |
| BUN [mg/dl] | 13.5 [7.78;18.5] | 24.0 [16.0;32.0] | 0.024 |
| Creatinine [mg/dl] | 0.90 [0.70;1.28] | 1.10 [0.90;1.75] | 0.010 |
| CRP [mg/dl] | 2.00 [0.60;4.53] | 5.30 [3.35;9.15] | < 0.001 |
| D-dimer [mg/dl] | 0.90 [0.50;2.89] | 0.90 [0.60;2.55] | 0.683 |
| Gamma-GT [U/l] | 36.0 [22.5;52.0] | 61.0 [28.0;106] | 0.025 |
| Interleukin-6 [pg/ml] | 15.4 [9.25;45.2] | 56.0 [30.9;89.3] | < 0.001 |
| INR | 1.00 [0.90;1.00] | 0.90 [0.90;1.00] | 0.746 |
| LDH [U/l] | 246 [213;306] | 313 [256;428] | 0.002 |
| Lymphocyte count [G/l] | 1.09 [0.83;1.45] | 0.86 [0.58;1.41] | 0.197 |
| Neutrophils count [G/l] | 3.12 [2.50;4.65] | 3.14 [2.70;5.09] | 0.656 |
| Troponin T [ng/ml] | 13.0 [13.0;14.0] | 18.5 [13.0;36.5] | 0.015 |
| Completed SARS-CoV-2 vaccination | 15 (21.7%) | 10 (28.6%) | 0.571 |