Fig. 4.

Reasons for inappropriate therapy after expert panel process. More than one reason for inappropriate therapy could be named: 111 reasons for inappropriate therapy regarding institutional standard; 141 reasons for inappropriate therapy regarding national guideline; ∗defined as more than 20% deviation from the corresponding recommendation of the institutional standard or the national guideline; ^#including no de-escalation, early escalation, delayed escalation, broad-spectrum therapy; ^§including prolonged therapy, missing indication.