Fig. 3.

Results of numerical simulations of fluid pressure and velocity in the MPA-chip with different geometries. (a) The total pressure drop over the chip when the distance between the pillars is the same for all the 9 rows (10 µm) or different (from 50 µm in the first row to 10 µm in the 9th row.) (b) The fluid velocity magnitude through the rows of the MPA-Chip, measured between the micropillar; the plot also includes the calculated the percentage of fluid velocity increase in the last two rows (after the 7th row) of the chip compared to the velocity increase over the whole chip (subtraction of outlet velocity from inlet velocity) for all geometries. The flow rate of the inlet blood was 2.5 ml/h. (c) Percentage of pressure drop over the last 2 rows and over all the 9 rows for all the geometries compared to the pressure drop over the whole chip (subtraction of outlet pressure from inlet pressure) for all geometries. (d) Pressure drop percentage per micrometer over all 9 rows and over the last 2 rows for all pillar geometries compared to the pressure drop over the whole chip (subtraction of outlet pressure from inlet pressure) for all geometries. (e-h) fluid pressure acting on trapped particles (15 µm) in the chip for (e) triangle (f) circle (g) rectangle (h) lozenge.