FIG. 1.

Mean C.I. of mutant strains for different tissues at 5 days postinoculation. Eight mice were orally infected with a mixture of WT and mutant strains in equal proportions. Tissues were harvested at 5 days postinoculation, homogenized, and plated on streptomycin, tetracycline, kanamycin, or chloramphenicol. Mean C.I.'s were determined as described in Materials and Methods. Each symbol is the logarithm of C.I. Solid squares, C.I.'s for the Δspi1::kan mutant; open circles, C.I.'s for the hilA::tet mutant; solid circles, C.I.'s for the invG::cam mutant. Horizontal lines are the mean of the logarithm of C.I.'s. ns, mean C.I. not significantly different from 1 (log C.I. = 0) (P > 0.05, one-sample t test). An asterisk indicates that a mean C.I. is significantly different from 1 (log C.I. = 0) (P < 0.05, one-sample t test).