TABLE 5.
GMV values across HCs, SCD, and aMCI groups.
Region (aal) | Peak MNI coordinate | F/t | Cluster number | ||
---|---|---|---|---|---|
x | y | z | |||
ANOVA | |||||
L middle frontal gyrus | −30 | 9 | 33 | 26.1047 | 143 |
R superior parietal lobule | 24 | −60 | 72 | 30.7415 | 112 |
R middle temporal gyrus | 39 | −60 | 12 | 27.6392 | 88 |
L superior frontal gyrus | −15 | 24 | 66 | 38.0666 | 85 |
SCD < HCs | |||||
R middle temporal gyrus | 39 | −60 | 12 | −7.7543 | 40 |
L superior frontal gyrus | −15 | 24 | 66 | −7.2529 | 35 |
R superior parietal lobule | 15 | −60 | 75 | −5.7876 | 24 |
aMCI < HCs | |||||
L superior frontal gyrus | −15 | 9 | 51 | −4.8495 | 43 |
R superior parietal lobule | 24 | −69 | 63 | −5.1014 | 30 |
SCD < aMCI | |||||
R middle temporal gyrus | 39 | −54 | 9 | −4.8384 | 72 |
R superior parietal lobule | 15 | −60 | 75 | −5.9125 | 57 |
L superior frontal gyrus | −15 | 24 | 66 | −8.7607 | 43 |
SCD > aMCI | |||||
L precentral gyrus | −36 | −3 | 33 | 5.8708 | 44 |
Note: Brain regions showed significant differences in GMV of the DAN across three groups (TFCE‐FDR corrected, cluster size >80 voxels, p < 0.05) and results of post hoc analysis in voxel‐wise analysis (Bonferroni corrected, cluster size >20 voxels, p < 0.05).
Abbreviations: aMCI, amnestic mild cognitive impairment; HCs, healthy controls; L, left; R, right; SCD, subjective cognitive decline.