TABLE 2.
Univariate Odds Ratios and 95% Confidence Intervals for Association Between Baseline Factors and Worse Outcomes in the Antibiotics-assigned/Selected Arm in the Combined Cohort
| Baseline Factor | Comparison | Regret | Dissatisfaction | Problems with Activities | Prolonged Missed Work |
|---|---|---|---|---|---|
| Age | Over 50 years vs. not | 1.35 (0.88,2.06) | 1.20 (0.73,1.99) | 1.78 (1.20,2.66) | 2.00 (1.09,3.65) |
| Sex | Female vs. male | 1.50 (1.05,2.14) | 1.93 (1.20,3.11) | 1.28 (0.90,1.83) | 1.34 (0.78,2.28) |
| BMI | (25, 30) vs. <25 | 1.08 (0.67,1.76) | 0.99 (0.55,1.78) | 1.24 (0.80,1.93) | 1.59 (0.82,3.09) |
| (30, 35) vs. <25 | 1.16 (0.69,1.97) | 0.62 (0.31,1.25) | 1.27 (0.76,2.15) | 2.22 (1.11,4.44) | |
| ≥35 vs. <25 | 1.47 (0.83,2.60) | 0.95 (0.46,1.93) | 1.88 (1.10,3.21) | 0.73 (0.24,2.24) | |
| Preferred language | Spanish vs. English | 0.98 (0.63,1.54) | 1.06 (0.64,1.74) | 0.92 (0.62,1.37) | 3.15 (1.83,5.43) |
| Health literacy help | Sometimes or more vs. never or rarely | 1.29 (0.82,2.04) | 0.78 (0.41,1.48) | 1.54 (1.00,2.37) | 1.34 (0.67,2.68) |
| Education | HS/GED or less vs. some beyond HS | 0.91 (0.61,1.36) | 0.68 (0.41,1.12) | 0.85 (0.60,1.20) | 2.40 (1.42,4.06) |
| Employment and activity | Employed (active) vs. employed (inactive) | 0.83 (0.54,1.29) | 1.15 (0.65,2.02) | 1.23 (0.81,1.86) | 1.50 (0.86,2.62) |
| Unemployed/student/other vs. employed (inactive) | 1.05 (0.68,1.61) | 1.23 (0.74,2.06) | 1.60 (1.07,2.40) | 1.57 (0.62,3.99) | |
| Below poverty or Medicaid/state program | Yes vs. no | 0.99 (0.63,1.55) | 0.90 (0.51,1.57) | 1.33 (0.94,1.89) | 2.77 (1.62,4.72) |
| Hispanic | Yes vs. no | 0.87 (0.59,1.29) | 0.85 (0.54,1.34) | 0.83 (0.58,1.17) | 2.27 (1.35,3.81) |
| Appendiceal diameter | For increase of 1mm | 1.07 (1.01,1.14) | 1.02 (0.95,1.10) | 1.06 (1.00,1.12) | 1.16 (1.07,1.26) |
| Perforation/abscess/fat | Yes vs. no | 1.00 (0.58,1.72) | 1.16 (0.59,2.28) | 1.01 (0.61,1.65) | 1.78 (0.89,3.57) |
| Appendicolith | Yes vs. no | 1.91 (1.31,2.77) | 1.45 (0.89,2.38) | 1.52 (1.01,2.29) | 1.92 (1.13,3.27) |
Odds ratios summarize association between baseline factors and odds of regret (decisional regret score over 50), dissatisfaction (somewhat or very dissatisfied with treatment for appendicitis), problems with activities (having problems performing usual activities, eg, work, housework, leisure), and prolonged missed work (missed more than 10 days of work, among those who were employed) at 30 days; bold text indicates that the confidence interval excludes 1, italic text indicates that the odds ratio is large (>2) or small (<0.5), considering a 1-standard deviation increase for continuous baseline factors; missing data in both the baseline factors and outcomes was addressed via multiple imputation; BMI, body mass index; GED, General Educational Development test credential; HS, high school.