Figure 2.

Characteristics of colonic IL-4⁺ ILC2s. (A) Differential gene expression in colonic ILC2s (Thy1.2⁺CD3⁻ KLRG1⁺ cells) and pulmonary ILC2s (Thy1.2⁺CD3⁻ ST2⁺ cells) sorted from SPF B6 mice. Heatmap colors represent the z-score normalized FPKM values for each gene. (B) Representative flow cytometry plots showing the expression of IL-17RB, KLRG1, ST2, and IL-4 by gated Thy1.2⁺Lin⁻GATA3⁺ cells in the colon, SI LP, and lungs. Data shown are representative of more than two independent experiments with n ≥ 3 individual mice per group.