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Normalized binding inhibition (%) for concentration-dependent inhibition of the S-RBD and ACE2 interaction by; pentosan polysulfate (PPS), Enoxaparin, and dAS-GAG oligosaccharide. A competition of S-ACE2 binding assay was performed by the RayBio® COVID-19 assay kit which uses a 96-well plate coated with recombinantly-expressed human ACE2 protein. The biological analysis was treated by ANOVA, p < 0.05 was selected prior to experiments to reflect statistical significance.
