Table 1.
Clinicopathological characteristics of 98 ESCC patients.
| Variables | Patient numbers | OTUs | Shannon index | Lactobacillus | Leptotrichia | ||||
|---|---|---|---|---|---|---|---|---|---|
| Mean | p | Mean | p | Mean | p | Mean | p | ||
| Sex Male Female |
73 (74.5%) 25 (25.5%) |
1,469.60 1,843.40 |
0.204 b | 6.16 6.56 |
0.249 b | 0.009 0.016 |
0.197 b | 0.024 0.015 |
0.150 b |
| Age (years)
a
≤59 >59 |
50 (51.0%) 48 (49.0%) |
1,524.00 1,607.63 |
0.719 b | 6.18 6.35 |
0.546 b | 0.010 0.012 |
0.502 b | 0.023 0.019 |
0.522 b |
| Smoking status Yes No |
56 (57.1%) 42 (42.9%) |
1,432.09 1,742.12 |
0.183 b | 6.04 6.56 |
0.078 b | 0.009 0.013 |
0.368 b | 0.022 0.020 |
0.718 b |
| Drinking status Yes No |
24 (24.5%) 74 (75.5%) |
1,460.00 1,599.00 |
0.572 b | 6.21 6.28 |
0.841 b | 0.008 0.012 |
0.407 b | 0.019 0.022 |
0.640 b |
| pTNM stage I-II III |
51 (52.0%) 47 (48.0%) |
1,562.06 1,568.11 |
0.979 b | 6.28 6.24 |
0.891 b | 0.012 0.010 |
0.554 b | 0.029 0.013 |
0.006 b |
| Invasion depth T1–2 T3–4 |
24 (24.5%) 74 (75.5%) |
1,626.54 1,544.99 |
0.779 b | 6.47 6.19 |
0.403 b | 0.013 0.010 |
0.590 b | 0.017 0.023 |
0.246 b |
| Tumor differentiation
c
Well Moderate Poor |
19 (19.4%) 50 (51.0%) 29 (29.6%) |
1,434.68 1,712.74 1,395.52 |
0.424 c | 6.19 6.34 6.18 |
0.873 c | 0.017 0.020 0.019 |
0.582 c | 0.020 0.027 0.013 |
0.183 c |
| Lymph node metastasis N+ N− |
52 (53.1%) 46 (46.9%) |
1,567.56 1,562.02 |
0.981 b | 6.21 6.32 |
0.705 b | 0.010 0.012 |
0.498 b | 0.030 0.014 |
0.011 b |
| Location
c
Upper Middle Lower |
11 (11.2%) 58 (59.2%) 29 (29.6%) |
1,827.73 1,493.50 1,608.21 |
0.656 c | 6.64 6.15 6.34 |
0.544 c | 0.021 0.010 0.008 |
0.191 c | 0.009 0.023 0.023 |
0.398 c |
Note. ESCC, esophageal squamous cell carcinoma; OTUs, operational taxonomic units.
a
Median was used as the cutoff value.
b
Students’ t-test.
c
ANOVA.
Bold values indicate statistically significant.