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Transcription expression of S100 proteins in various cancers and HNSCC. (A) Number of datasets with statistical significance for S100s mRNA expression in different types of cancers: red, upregulated; blue, downregulated. (B) mRNA expression distribution of S100 proteins in HNSCC tumor tissues and normal tissues. *, P<0.05; **, P<0.01; ***, P<0.001; -, not significant; CNS, central nervous system; mRNA, messenger RNA; HNSCC, head and neck squamous cell carcinoma.
