ZNF687 overexpression relates to poor prognosis in lung adenocarcinoma (LUAD) patients. (a, b) ZNF687 protein expression levels were analyzed utilizing western blotting in eight cases of fresh LUAD tumor and matched adjacent tissue specimens. (***p < 0.001, ****p < 0.0001). (c) ZNF687 expression in paraffin‐embedded pathological specimens of 20 paired LUAD and paracarcinoma tissues was identified via immunohistochemistry (IHC) examination (scale bars, 100 and 50 μm, respectively). (d) ZNF687 expression in the tissue microarray, which contained 98 pairs of LUAD samples and 82 pairs of their paracarcinoma tissues detected via IHC analysis (scale bars, 625, 100, and 50 μm, respectively). (e) Kaplan–Meier plotter survival analysis depended on microarray tissue IHC outcomes including 87 patients with LUAD (low vs. high expression; p < 0.001).