Figure 1.

Genetic analyses of RSV infection in infancy. A, The Manhattan plot shows no genome-wide significant associations (P value threshold of 5e⁻⁸). B, The Q-Q plot demonstrates that the observed P values are congruent with those expected under the null hypothesis that RSV infection in infancy is independent of host genotype. C, The association between the 54 selected childhood asthma- or RSV lower respiratory tract infection-associated SNPs and RSV infection in infancy in our data. The solid diagonol identity line (shown in red), and the dashed grey lines are ±1 standard deviation around the expected −log₁₀ (P value). Abbreviations: RSV, respiratory syncytial virus; SNP, single nucleotide polymorphism.