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. 2023 May 11;381(4):16. doi: 10.1007/s41061-023-00426-9

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© The Author(s) 2023

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 13 — a Schematic illustration of the mouse lung anatomy and imaging MS. a—Mouse lung anatomy. b—Imaging MS (IMS), which allows visualization of the distribution and abundance of a target molecule in biological tissue. The figure is from an open access article distributed under the terms of the Creative Commons CC BY license. Copyright © 2020. Springer, Nature. b Signal of ACh and amount-dependent signal intensity. a—ACh chemical structure (the theoretical exact mass is 146.1181). b—Comparison of ACh signal peaks for the standard and lung tissue. c—The ACh abundance dilution of the standard on lung tissue in spots visualized by Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR-MS). The figure is from an open access article distributed under the terms of the Creative Commons CC BY license. Copyright © 2020. Springer, Nature