Table 2.
Summary of adipose-derived therapeutics.
Type of therapeutics | Advantages | Disadvantages |
---|---|---|
SVF | • easy to isolate (point-of-care isolation) • no need of cell sorting and cell culture |
• heterogenous cell composition • difficult to standardize and characterize • vary in composition and quantity depending on the host’s condition and isolation method |
AD-MSC | • more defined characteristics • efficacy can be manipulated by preconditioning |
• requirement of cell culture • potential phenotypic changes and senescence upon cell culture |
secretome | • cell-free reagent • safe and low immunogenicity |
• potential requirement of cell culture • isolation and characterization can be time-consuming |