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. 2023 Apr 28;14:1111813. doi: 10.3389/fimmu.2023.1111813

Table 2.

Summary of adipose-derived therapeutics.

Type of therapeutics Advantages Disadvantages
SVF • easy to isolate (point-of-care isolation)
• no need of cell sorting and cell culture
• heterogenous cell composition
• difficult to standardize and characterize
• vary in composition and quantity depending on the host’s condition and
  isolation method
AD-MSC • more defined characteristics
• efficacy can be manipulated by preconditioning
• requirement of cell culture
• potential phenotypic changes and senescence upon cell culture
secretome • cell-free reagent
• safe and low immunogenicity
• potential requirement of cell culture
• isolation and characterization can be time-consuming