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. 2023 Apr 28;14:1105427. doi: 10.3389/fphar.2023.1105427

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Copyright © 2023 Liu, Wang, Huang, Rutz, Ciotkowska, Tamalunas, Hu, Trieb, Waidelich, Strittmatter, Stief and Hennenberg.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of NUAK silencing, HTH01-015 and WZ4003 on proliferation of WPMY-1 cells. Proliferation was assessed 48 h after transfection with scramble siRNA of isoform-specific NUAK siRNAs (A,B), or 36 h after addition of HTH01-015, WZ4003 or solvent to controls (C–E) as the content of Ki-67 mRNA (A,C) or by EdU assays (B,D,E). Shown are scatter plots including all single values from each independent experiment together with p values from one-way ANOVA with Tukey’s test in (B) and one-way ANOVA with Dunnett’s test in all other panels, and representative experiments from EdU assays.