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Activation of striatal microglia is involved in TS. (A) The TS group has a trend toward increased Iba-1 positive cells, with asymmetrical branches and an amoeba-like appearance. (B) The levels of inflammatory factors TNF-α, IL-6, IL-10, and iNOS are significantly increased in the striatum of TS individuals, while the M2 marker Arg-1 is decreased. *P <0.05, **P <0.01, ***P <0.001.
