Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 May 1;120(19):e2216268120. doi: 10.1073/pnas.2216268120

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2023 the Author(s). Published by PNAS.

This open access article is distributed under Creative Commons Attribution License 4.0 (CC BY).

PMC Copyright notice

Fig. 4. — Surge of functional connectivity across multiple frequency bands in the dying patients. (A) Temporal dynamics of functional connectivity between the right posterior temporal lobe (T6) and the right parietal lobe (P4) of Pt1. (B) Spatial and temporal dynamics of functional connectivity across the dying brain over six indicated frequency bands in Pt1. (C) Temporal changes of functional connectivity in beta, gamma1, and gamma2 bands for the six indicated combinations within the TPO junctions are shown for Pt1 for the entire duration (S1 to S11). (D) Gamma1 coherence in S2 within the left (lTPO) and right (rTPO) TPO junctions for both Pt1 (P < 0.05) and Pt3 (P < 0.05). Two-tailed unpaired t tests were carried out to determine the statistical significance between the averaged coherence within the left TPO junctions (O1P3, O1T5, P3T5) and those within the right TPO junctions (O2P4, O2T6, P4T6). (E) Gamma1 coherence within the TPO junctions before (S1) and following ventilator withdrawal (S2) in both Pt1 (P < 0.01) and Pt3 (P < 0.01). Two-tailed paired t tests were carried out on the averaged TPO coherence between S1 and S2. (F) Long-range gamma1 synchrony between each of the TPO components (temporal, parietal, and occipital lobes) and each of the prefrontal lobes at near-death in Pt1. The interhemispheric coherence pairs are displayed as solid circles and lines, whereas the intrahemipheric coherence pairs as solid triangles and dashed lines. (G) Interhemispheric (contra; solid black boxes) versus intrahemispheric (ipsi; open boxes) gamma1 coherence at near death (S4 for Pt1, S3 for Pt3) in both Pt1 (P < 0.001) and Pt3 (P < 0.001). The interhemispheric coherence was compared with intrahemispheric coherence using two-sided unpaired t tests. (H) Long-range gamma1 coherence at baseline (S1) and near-death (ND, S4 for Pt1, S3 for Pt3) within the same hemisphere (Intrahemisphere) or cross the midline (Interhemisphere) for Pt1 and Pt3. (P < 0.001). Two-sided paired t tests were carried out for the statistic values displayed.