Table 2.

Laboratory findings in SIDS cases (for references see refs. ^48–50).

Mild acute inflammatory changes in airways, lungs, and myocardium

Proteomic and immunohistochemical evidence of infection and responses to infection bacterial toxins in tissues

IgG response to bacterial toxins

Increased IgM response to core endotoxin

Increased levels of mast cell tryptase

Increased levels of mannose-binding lectin

Raised fibrin degradation products

CD68 immunoreactivity in airways and brain

Raised IL-6 in vitreous humour, cerebrospinal fluid, and liver

CSF lymphocytosis

Presence of tracheal/lung IgM

IL-10 low producer

IL-1b high producer

Raised IgA in duodenum and saliva

Normally sterile site cultures yielding a bacterial pathogen