FIG. 3.

(a) Activation of plasminogen by M. tuberculosis SE (▴) and WSS (▵) in fibrin matrices and by fibrin in the absence of mycobacterial extracts (⧫). Also shown are assays with WSS carried out in wells devoid of fibrin matrices (○). Results are expressed as the percent of the maximal activation induced by streptokinase (●). (b) Assays carried out in wells covered with fibrin matrices with WSS (○), with WSS plus α₂-antiplasmin (●), and with WSS after boiling (∗). Results are expressed as the percent of activation induced by WSS. Results of a representative experiment are presented. Experiments (n = 3) were carried out in triplicate, and the data are presented as means ± standard deviations (error bars).