Correlation analysis of N-glycopeptides and glycosylation enzymes.A, heatmap showing the expression of glycosylation-associated transferase, transporter, glucosidase, and hydrolase in RA and OA synovial tissues based on the proteomics data (Student’s t test, ∗p < 0.05; ∗∗p < 0.01). B, bubble chart shows differentially expressed N-glycopeptides and glycosylation enzymes with significant linear correlation (Spearman's rank correlation coefficient, p < 0.05). C, representative differentially expressed N-glycopeptides linearly correlated with glycosylation enzymes. R represents the regression coefficient and the p value represents the significance of the linear correlation. OA, osteoarthritis; RA, rheumatoid arthritis.