Table 3. Audiometric Findings Among EPIC-PCD Participants, Overall and by Age Group.
| Hearing loss gradea | No. (%) | ||||||
|---|---|---|---|---|---|---|---|
| Total (N = 273) | Age 0-6 y (n = 18) | Age 7-14 y (n = 84) | Age 15-30 y (n = 110) | Age 31-50 y (n = 41) | Age >50 y (n = 20) | Affected ears (N = 546) | |
| Normal hearing (≤25 db) | |||||||
| Bilateral | 154 (56) | 7 (39) | 53 (63) | 77 (70) | 17 (41) | 0 | 341 (63) |
| Unilateral | 33 (12) | 1 (6) | 12 (14) | 14 (13) | 4 (10) | 1 (5) | |
| Mild hearing loss (26-40 dB) | |||||||
| Bilateral | 55 (20) | 8 (44) | 12 (14) | 13 (12) | 14 (34) | 8 (40) | 158 (29) |
| Unilateral | 48 (18) | 1 (6) | 15 (18) | 17 (15) | 9 (22) | 6 (30) | |
| Moderate hearing loss (41-60 dB) | |||||||
| Bilateral | 7 (3) | 1 (6) | 2 (2) | 0 | 1 (2) | 3 (15) | 35 (6) |
| Unilateral | 21 (8) | 1 (6) | 4 (5) | 6 (5) | 5 (12) | 5 (25) | |
| Severe hearing loss (61-80 dB) | |||||||
| Bilateral | 1 (0) | 0 | 0 | 0 | 0 | 1 (5) | 6 (1) |
| Unilateral | 4 (1) | 0 | 1 (1) | 0 | 0 | 3 (15) | |
| Profound hearing loss (≥81 dB) | |||||||
| Bilateral | 1 (0) | 0 | 1 (1) | 0 | 0 | 0 | 3 (0) |
| Unilateral | 1 (0) | 0 | 0 | 1 (1) | 0 | 0 | |
| Could not be performedb | 3 (1) | NA | NA | NA | NA | NA | 3 (0) |
Abbreviations: EPIC-PCD, Ear-Nose-Throat Prospective International Cohort of patients with primary ciliary dyskinesia; NA, not applicable.
a
Hearing loss grades are based on the World Health Organization hearing loss grading system. Categories are not exclusive because participants can have different hearing loss grades in each ear.
b
In 3 patients, audiometry was recorded as not performed due to technical reasons for 1 of the ears.