TABLE 1.

In Vivo Oxygen Depletion Results Summary

Dose rate	Tissue type	Initial pO2 (mmHg)	pO2 depleted (mmHg)	G value (mmHg)	Recovery time (s)	Recovery rate (mmHg)	Number of mice
FLASH
	Normal
	Male	32.78 ± 2.34	8.71 ± 0.18	0.29 ± 0.01	9.90 ± 0.51	0.89 ± 0.05	n = 4
	Female	26.94 ± 1.27	8.19 ± 0.43	0.27 ± 0.01	5.15 ± 0.30	1.59 ± 0.04	n = 3
	Combined	30.27 ± 1.79	8.50 ± 0.22	0.28 ± 0.01	7.86 ± 1.00	1.19 ± 0.15	n = 7
	Tumor
	Male	16.06 ± 2.74	3.49 ± 0.54	0.12 ± 0.02	26.00 ± 4.93	0.15 ± 0.03	n = 5
	Male laser diode	16.13 ± 5.46	3.85 ± 1.12	0.13 ± 0.04	30.25 ± 5.11	0.13 ± 0.03	n = 4
Conventional
	Normal muscle
	Male	37.7	−0.83*	−0.03*	NA	NA	n = 1
	Female	32.92 ± 2.64	0.88 ± 0.19	0.03 ± 0.01	NA	NA	n = 3
	Combined	34.11 ± 2.21	0.46 ± 0.44	0.02 ± 0.01	NA	NA	n = 4
	Tumor
	Male	8.87 ± 1.06	−0.78 ± 0.07*	−0.03 ± 0.00*	NA	NA	n = 3
FLASH 60 Gy
	Normal muscle
	Male	8.87 ± 7.27	13.50 ± 1.67	0.22 ± 0.03	8.10 ± 0.62	1.71 ± 0.31	n = 3

Note. Gender specific and aggregate data sets for normal and tumor tissue irradiated at both FLASH and Conv dose rates. Data shown is mean ± SEM.

^*Negative values denote an increase in pO₂ during irradiation.