Table 1:

Comparison of all cases by primary (1R) versus repeat resections (≥2R).

	1R (N=369)	≥2R (N=105)	p-value
Patient and Disease Characteristics
Male (%)	264 (71.5)	67 (63.8)	0.16
Age (median [IQR])	31 [24, 46]	43 [31, 54]	<0.001
BMI (median [IQR])	22.3 [19.7, 25.8]	22.0 [19.5, 26.0]	0.68
ASA ≥ 3 (%)	108 (29.3)	39 (37.1)	0.16
Smoker (%)			<0.001
Never	340 (92.1)	77 (73.3)
Former	17 (4.6)	18 (17.1)
Current	12 (3.3)	10 (9.5)
Indication for surgery (%)			0.69
Obstruction	272 (73.7)	80 (76.2)
Abscess	68 (18.4)	17 (16.2)
Fistula	11 (3.0)	4 (3.8)
Dysplasia	8 (2.2)	0 (0.0)
Failure of medical therapy	5 (1.4)	2 (1.9)
Other*	5 (1.4)	2 (1.9)
Phenotype (%)			0.21
Inflammatory	14 (3.8)	3 (2.9)
Stricturing	202 (54.7)	67 (64.4)
Penetrating	153 (41.5)	34 (32.4)
History of other abdominal surgery (%)	55 (14.9)	28 (26.7)	0.01
Perioperative steroids (%)	45 (12.2)	17 (16.2)	0.36
Perioperative biologics (%)	50 (13.6)	18 (17.1)	0.44
Operative Characteristics
Emergency surgery (%)	9 (2.4)	3 (2.9)	0.73
Extended ICR** (%)	37 (10.0)	3 (2.9)	0.02
Concurrent procedures (%)	195 (52.8)	59 (56.2)	0.62
Approach (%)			<0.001
Laparoscopic	314 (85.1)	75 (71.4)
Converted	32 (8.7)	8 (7.6)
Open	23 (6.2)	22 (21.0)
Diverting stoma (%)	16 (4.3)	5 (4.8)	0.79
Duration, minutes (median [IQR])	120 [94, 157]	145 [101, 206]	<0.001
Postoperative Outcomes
Length of stay, days (median [IQR])	5 [4, 7]	6 [5, 9]	0.02
Any complication (%)	52 (14.1)	21 (20.0)	0.19
Major complication (%)	14 (3.8)	4 (3.8)	0.56
30-day readmission (%)	14 (3.8)	3 (2.9)	0.77
Reoperation (%)	11 (3.0)	0 (0.0)	0.13

^*Perforation, toxic megacolon, hemorrhage, recurrent appendicitis

^**Any additional distal bowel margin beyond the cecum