Table 1.

Sensitivity analysis of the causal association between IBD and kidney function

Exposure	Outcomes	Cochran Q test		MR–Egger		MR–PRESSO
		Q value	P	Intercept	P	P value
UC	eGFRcrea	98.03	0.022	−0.0002	0.09	0.26
	uACR	101.31	0.019	0.0004	0.62	0.002
	Urolithiasis	105.59	0.011	−0.004	0.54	0.79
	IgA nephropathy	84.62	0.26	−4.49 × 10–6	0.99	0.43
	CKD	112.62	0.0078	0.0003	0.92	0.64
CD	eGFRcrea	198.16	9.31 × 10–10	−3.86 × 10–5	0.81	0.70
	uACR	194.11	2.63 × 10–8	4.7 × 10–5	0.96	0.19
	Urolithiasis	161.52	0.0001	0.0046	0.48	0.019
	IgA nephropathy	116.99	0.164	0.0022	0.57	0.83
	CKD	146.29	0.0048	0.0017	0.61	0.06