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. 2023 Apr 25;15(9):2446. doi: 10.3390/cancers15092446

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Summary of the newly identified diagnostic liquid biomarkers for PDAC. The newly identified liquid biomarkers for improving the sensitivity as well as the specificity of PDAC at its early stage were illustrated. The improved detection sensitivity indicated was in comparison with that using CA19-9 alone. LRG: leucine-richalpha-2 glycoprotein; TIMP: tissue inhibitor matrix metalloproteinase; MIC: macrophage inhibitory cytokine; CIB: calcium and integrin binding; TNP: transition protein; RIT2: RaslikewithoutCAAX2.