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. 2023 May 5;12(9):1315. doi: 10.3390/cells12091315

Table 1.

Functions of miR-183 in cancers.

Cancer Regulation Tissue No. Cell Lines Functions Target Gene Source
NSCLC × × H157, 344SQ (mouse) Inhibit EMT, migration, and invasion Foxf2 [31]
NSCLC Up n = 8 NCL-H292, NCL-H838, MRC-5, WI-26 VA4 Promote occurrence and invasion TFAP2C [47]
NSCLC Up n = 76 A549, H226, BEAS-2B, H1395 Promote proliferation × [48]
NSCLC Up n = 55 A549, SPC-A-1, H1299 Promote migration and proliferation PTEN [35]
Lung cancer Up × H1299 Promote EMT and radioresistance ZEB1 [36]
NSCLC Up n = 194 SPC-A-1 Inhibit EMT, migration, and proliferation MTA1 [44]
CRC Up n = 94 × Invasion × [30]
CRC Down × HCT116, HT29 Promote apoptosis UVRAG [37]
PCa Up n = 50 × × × [33]
PCa Up × LNCaP, PC-3 Promote migration, proliferation, and invasion TPM1 [38]
PCa Down n = 12 Vcap, C4-2 Inhibit proliferation and migration. Promote apoptosis HMGN5 [39]
GC Down n = 102 BGC823, MKN45 Inhibit proliferation and migration EEF2 [40]
GC Up n = 24 GES-1, MKN-7, AGS, HGC-27 Promote migration and invasion TPM1 [42]
GC Down × MKN28 Inhibit invasion UVRAG [41]
HCC Down n = 10 HepG2 Inhibit proliferation and migration MTA1 [45]
OS Down n = 40 × Associated with progression and metastasis of osteosarcoma × [34]
OS Down n = 25 MG63 Inhibit the vitality, invasion and migration MTA1 [46]

×: No relevant data or assays using pathological tissue or cell lines.