Table 2.
The most common immunohistochemistry markers expressed in the different types of liver cancer.
| Marker | iCCA | HCC | Liver Metastases | p Value |
|---|---|---|---|---|
| CK7, n (%) * | 59 (93.7) | 1 (14.3) | 25 (80.6) | <0.001 |
| CK19, n (%) | 43 (100) | 3 (37.5) | 6 (54.5) | <0.001 |
| CEA, n (%) | 19 (82.6) | 4 (44.4) | 5 (50) | <0.001 |
| CA19-9, n (%) | 9 (100) | 0 | 6 (100) | <0.001 |
| Hep Par 1, n (%) | 1 (3.3) | 55 (98.2) | 0 | <0.001 |
| Glypican 3, n (%) | 1 (16.7) | 44 (100) | 0 | <0.001 |
| CD34, n (%) | 3 (37.5) | 54 (100) | 0 | <0.001 |
| CDX2, n (%) | 12 (28.6) | 0 | 36 (94.7) | <0.001 |
| CK20, n (%) | 4 (9.8%) | 0 | 18 (94.7) | <0.001 |
In blue—the most frequently expressed markers in intrahepatic cholangiocarcinoma; in red—the most frequently expressed markers in hepatocellular carcinoma; in green—the most frequently expressed markers in liver metastases from colorectal carcinoma; HCC = hepatocellular carcinoma, iCCA = intrahepatic cholangiocarcinoma; n = number, % = per cent; p = level of significance, CK = cytokeratin; CA = carcinogenic antigen; CEA = carcinoembryonic antigen; CD = cluster of differentiation; * a marker expressed in both iCCA and liver metastases from colorectal carcinoma.