Figure 6.
Impact of IVIg treatment on ex vivo Dsg3-specific proliferation response of splenocytes. (A) 3H-T-based cell-proliferation analysis. (B) IFN-γ-specific type 1 T-cell response using ELISpot analysis. Statistical significance was performed using the unpaired t test with Welch’s correction. p ≤ 0.05. (up-regulation or * down-regulation, respectively). Error bars in graphs represent standard deviation, mean ± SD. n = 6–8 mice per group. A1–3 = prevention protocol, B1–3 = quasi-therapeutic protocol.