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. 2023 May 6;15(9):2632. doi: 10.3390/cancers15092632

Figure 1.

Figure 1

Sensitivity test for LNA-clamp PCR. Comparison of the sensitivity with serially diluted Y537S mutant DNA (1, 3, 10, 33, and 100 copies) in wild-type DNA (with or without clamp; the references are 100,000 copies and 10,000 copies, respectively). The input mutant copy number (log) was plotted on the X-axis and the output mutant copy number (log) was plotted on the Y-axis. The samples with the LNA oligo (clamp: red line), without the LNA oligo (no clamp: blue line), and the reference (black line) are shown. Error bars indicate the standard deviation over 10 experiments.