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FIG. 6.

FIG. 6

Effects of anti-IFN-γ treatment on parasite loads in footpads of C57BL/6 mice infected with 102 L. major metacyclic promastigotes. Mice were treated at the time of challenge and then on a weekly basis with 1 mg of XMG-6/mouse (◊) or with anti-β-galactosidase (GL113) (□). Results are expressed as the geometric mean number of viable amastigotes ± 1 standard deviation; 4 to 5 mice per group were used. The asterisk indicates the significant difference between values at the indicated time point (P < 0.05).