TABLE 1.
Antigen-specific IFN-γ production by lymph node cells from mice infected with a high or low dose of L. major
| Week postinoculation | Production of IFN-γ (pg/ml) witha:
|
|
|---|---|---|
| Low dose (102) | High dose (106) | |
| 3 | 0 | 1,541 ± 544 |
| 5 | 189 ± 156 | >2,000 |
| 7 | 1,970 ± 585 | 2,153 ± 1,468 |
a
Values are means ± the standard deviations of IFN-γ levels in supernatants from antigen-stimulated cultures minus results for medium controls. Six mice per group were used, and results were pooled from two separate experiments.