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. 2023 Apr 23;15(9):2420. doi: 10.3390/cancers15092420

Table 2.

Differentially expressed miRNAs in uterine leiomyosarcomas vs. normal uteri and benign uterine tumors.

miRNA Differential Expression Reference
miRNA-23b Downregulation in endometrial sarcomas
No statistically significant changes between leiomyosarcomas
and normal uteri
[44]
miRNA-1
let-7f
let-7c
miRNA-221 Upregulation in leiomyosarcoma
Absence in leiomyoma and benign metastasizing leiomyoma
[45]
miRNA-133a Upregulation in leiomyosarcoma [46]
miRNA-133b
miRNA-1
miRNA-1 Strong suppression in leiomyosarcoma [47]
miRNA-4430 Downregulation in leiomyosarcoma [48]
miRNA-6511b-5p
miRNA-451a
miRNA-4485-5p
miRNA-4635
miRNA-1246
miRNA-191-5p
miRNA-126 Downregulation in leiomyosarcoma
Hypo-expression between uterine leiomyoma and benign
metastasizing leiomyoma
[49]
miRNA-221 Upregulation in leiomyosarcoma [49]