Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Apr 27;12(9):1269. doi: 10.3390/cells12091269

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

(A) Comparison of propranolol P_app estimates in canine colonoid vs. human Caco-2 monolayers as a function of transport direction (AP-BL vs. BL-AP) and apical pH (6.8 vs. 7.4). (B) Comparison of metoprolol (0.04 mg/mL) P_app estimates in canine colonoid vs. human Caco-2 monolayers as a function of transport direction (AP-BL vs. BL-AP) and apical pH (6.8 vs. 7.4). (C) Comparison of metoprolol (0.4 mg/mL) P_app estimates in canine colonoid vs. human Caco-2 monolayers as a function of transport direction (AP-BL vs. BL-AP) and apical pH (6.8 vs. 7.4). (D) Comparison of atenolol (2 mg/mL) P_app estimates in canine colonoid vs. human Caco-2 monolayers as a function of transport direction (AP-BL vs. BL-AP) and apical pH (6.8 vs. 7.4).

(A) Comparison of propranolol P_app estimates in canine colonoid vs. human Caco-2 monolayers as a function of transport direction (AP-BL vs. BL-AP) and apical pH (6.8 vs. 7.4). (B) Comparison of metoprolol (0.04 mg/mL) P_app estimates in canine colonoid vs. human Caco-2 monolayers as a function of transport direction (AP-BL vs. BL-AP) and apical pH (6.8 vs. 7.4). (C) Comparison of metoprolol (0.4 mg/mL) P_app estimates in canine colonoid vs. human Caco-2 monolayers as a function of transport direction (AP-BL vs. BL-AP) and apical pH (6.8 vs. 7.4). (D) Comparison of atenolol (2 mg/mL) P_app estimates in canine colonoid vs. human Caco-2 monolayers as a function of transport direction (AP-BL vs. BL-AP) and apical pH (6.8 vs. 7.4).