Table 2.
Baseline characteristics of asthma patients before registration on the digital asthma platform
| Inactive users n = 41 |
Active users n = 106 |
p-value | |
|---|---|---|---|
| Age, mean (SD) | 45 (17) | 47 (13) | 0.40 |
| Female, n (%) | 33 (80) | 80 (75) | 0.52 |
| BMI, mean (SD) | 28.0 (6.2) | 29.1 (7.4) | 0.39 |
| Reflux, n (%) | 5 (12) | 31 (29) | 0.034 |
| Atopic dermatitis, n (%) | 16 (39) | 26 (25) | 0.081 |
| Nasal polyposis, n (%) | 16 (39) | 27 (25) | 0.11 |
| CRSwNP/CRSsNP, n (%) | 22 (54) | 58 (55) | 0.91 |
| Allergic rhinitis, n (%) | 19 (46) | 48 (45) | 0.91 |
| Bronchiectasis, n (%) | 2 (5) | 11 (10) | 0.52 |
| Hypertension, n (%) | 9 (22) | 32 (30) | 0.32 |
| COPD, n (%) | 1 (2) | 4 (4) | 0.99 |
| Diabetes mellitus, n (%) | 2 (5) | 10 (9) | 0.51 |
| Coronary artery disease, n (%) | 0 (0) | 1 (1) | 0.99 |
| Atrial fibrillation, n (%) | 1 (2) | 4 (4) | 0.98 |
| Hypothyroidism, n (%) | 3 (7) | 14 (13) | 0.40 |
| Obstructive sleep apnea, n (%) | 4 (10) | 21 (20) | 0.22 |
| Osteoporosis/osteopenia, n (%) | 3 (7) | 18 (17) | 0.19 |
| Depression, n (%) | 11 (27) | 21 (20) | 0.36 |
| Anxiety, n (%) | 4 (10) | 21 (20) | 0.22 |
| FEV1 liter, mean (SD) | 2.70 (0.73) | 2.75 (0.81) | 0.73 |
| FVC liter, mean (SD) | 3.58 (0.84) | 3.67 (0.87) | 0.60 |
| FEV, mean (SD) | 0.75 (0.10) | 0.74 (0.13) | 0.77 |
| Smoking status, n (%) | 0.45 | ||
| Never smoked | 36 (88) | 82 (77) | |
| Ex-smoker | 5 (12) | 23 (22) | |
| Smoker | 0 (0) | 1 (1) | |
| Positive skin prick test or elevated allergen-specific serum IgE, n (%) | 23 (56) | 64 (64) | 0.38 |
| Serum IgE kU/liter, median (IQR) | 84 (32, 306) [31] | 74(23, 283) [82] | 0.65 |
| Exhaled NO ppb, mean (SD) | 29.3 (39.8) [14] | 34.1 (34.1) [34] | 0.72 |
| Blood eosinophil count E9/liter, mean (SD) | 0.31 (0.31) [23] | 0.21 (0.24) [78] | 0.11 |
| ACT, maximal score 25, mean (SD) | 17.2 (5.3) [27] | 17.1 (4.8) [56] | 0.98 |
| Daily OCS medication, n (%) | 5 (12) | 22 (21) | 0.23 |
| GINA, n (%) | 0.024 | ||
| step 1 | 2 (5) | 0 (0) | |
| step 2 | 2 (5) | 1 (1) | |
| step 3 | 3 (7) | 11 (10) | |
| step 4 | 17 (41) | 28 (26) | |
| step 5 | 17 (41) | 66 (62) | |
| Biological asthma therapy, n (%) | 9 (22) | 28 (26) | 0.58 |
[n] represents the number of patients with available data when there were missing data. SD = standard deviation. ACT = asthma control test. FEV1 = forced expiratory volume in one second. FVC = forced vital capacity. FEV = forced expiratory volume ratio. NO = nitric oxide. ppb = part per billion. BMI = body mass index. IgE = immunoglobulin E. IQR = interquartile range. CRSwNP = chronic rhinosinusitis with nasal polyposis. CRSsNP = chronic rhinosinusitis without nasal polyposis. COPD = chronic obstructive pulmonary disease. OCS = Oral corticosteroids. GINA = Global Initiative for Asthma