TABLE 3.
Cytokine | No. with positive smear/total (%)a
|
P | |
---|---|---|---|
Responderb | Nonresponder | ||
IL-5 | 11/25 (44.0) | 23/44 (52.3) | NSc |
IL-10 | 4/16 (25.0) | 30/61 (49.2) | 0.083 |
IFN-γ | 20/43 (46.5) | 24/51 (47.1) | NS |
TNF-α | 6/14 (42.9) | 20/40 (50.0) | NS |
Blood smear positive for P. falciparum at any time in the 10 weeks following treatment.
A responder is defined as an individual with a cytokine level greater than the mean + 2 SD of North American control subjects.
χ2 test; NS, not significant.