Figure 8.

Cell viability measurement by MTT assay (A,B) and trypan blue exclusion assay (C,D) on co-cultures of SH-SY5Y and U373 or U373-Tat cells untreated or treated with 100 μg/mL Nat- or Holo-bLf for 24 h. The histograms in (A,B) show the percentage of living cells, and the rate of reduction was calculated by setting the control (CTRL) equal to 100%. One-way ANOVA, followed by Tukey’s test, was used to determine significant differences. * p ≤ 0.05 and **** p ≤ 0.0001 vs. CTRL; ° p ≤ 0.05 and °°° p ≤ 0.001 vs. Tat; ^ p ≤ 0.05 and ^^^^ p ≤ 0.0001 between Tat and CTRL.