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. 2023 Apr 14;14:1131662. doi: 10.3389/fmicb.2023.1131662

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Copyright © 2023 Van den Abbeele, Deyaert, Thabuis, Perreau, Bajic, Wintergerst, Joossens, Firrman, Walsh and Baudot.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Case study 1: Average levels (n = 6) of microbial phylum [proportional (A)/absolute (C)] and SCFA (F) for the in vivo-derived inocula (INO) and upon 24 h of incubation in the SIFR^® technology (NSC or IN treatment). The families that were significantly affected by IN treatment, either when statistics were based on proportional and absolute data are shown in, respectively, (B,D) (expressed as log₂(ratio of abundance upon IN treatment compared to NSC), along with the corresponding adjusted p-value). Further, IN also significantly impacted the absolute levels of several species (E), resulting in marked correlations between specific species and metabolic markers (threshold >0.8) (G).