a
|
|
A549 |
human lung cells |
ACE2 |
angiotensin-converting enzyme 2 |
AKT-mTOR signaling |
protein kinase B-mammalian target of rapamycin complex |
APCs |
antigen presenting cells |
Arl8b |
Arf-like GTPases |
ARP2/3 |
actin-related protein 2/3 complex |
ARH-77 |
B lymphoblast cell line |
ASC |
adaptor apoptosis-associated speck-like protein with a caspase-1 recruitment domain |
ATG
|
autophagy-related genes |
ATP6AP1 |
S1 subunit of the enzyme V-type proton ATPase. |
b
|
|
BCL-xL |
B-cell lymphoma-extra large |
BECN1(Beclin-1) |
mammalian ortholog of the yeast autophagy-related gene 6 |
BORC-ARL8b |
complex multisubunit complex- regulates lysosome positioning |
c
|
|
Calu-3 |
human bronchial epithelial cells |
CARD |
caspase recruitment domain |
CatB/L |
cathepsin B and L |
CAV |
Coxsackie viruses |
c-Myc |
proto-oncogene |
CNS |
central nervous system |
CXCR-4 |
C-X-C chemokine receptor type 4 |
d
|
|
3D organoids |
miniature 3-dimensional structures that can mimic the structure and function of different tissues |
DAMPs |
damage-associated molecular patterns |
DENV |
Dengue virus |
DMV |
double-membrane vesicles |
Dolutegravir |
antiretroviral medication |
e
|
|
EBV |
Epstein Bar virus |
eIF2a |
translation elongation factor |
Emtricitabine |
nucleoside reverse-transcriptase inhibitor |
ER |
endoplasmic reticulum |
f
|
|
FAM134 |
reticulon protein- ER-phagy receptor |
g
|
|
GABARAP |
GABA type receptor-associated protein |
GSDMD |
gasdermin D |
GTPase |
hydrolase enzyme binding nucleotide guanosine triphosphate |
h
|
|
HCV |
hepatitis C virus |
HEK 293T |
human embryonic kidney cells |
HIF-1 |
hypoxia-induced transcription factor-1 |
Hsc70 |
heat shock cognate 71 kDa protein |
HSV |
herpes simplex virus type I |
HOPS |
homotypic fusion and protein sorting |
i
|
|
ICP34.5 |
infected cell protein 34.5 |
IFN |
interferon |
iPSCs |
human induced pluripotent stem cells |
j
|
|
JAK1/2 |
Janus kinase- (tyrosine kinases) |
k
|
|
KSHV |
Kaposi’s sarcoma-associated herpes virus |
l
|
|
LAMP1 |
lysosomal associated membrane glycoprotein 1 |
LAMP2A |
lysosomal associated membrane protein 2 |
LC3 |
microtubule associated protein 1 light chain 3B |
LIR |
LC3-interacting region |
Lopinavir |
antiretroviral protease inhibitor |
m
|
|
MAVS |
mitochondrial antiviral-signaling protein |
MCL-1 |
induced myeloid leukemia cell differentiation protein |
MHC |
major histocompatibility complex |
MHV |
murine hepatitis virus |
mTORC1/S6K/4EBP1 |
mammalian target of rapamycin complex 1/p70 ribosomal S6 kinases/4E-binding protein 1 |
n
|
|
NBR1 |
neighbor of BRCA1 gene |
NCI-BL 2171 |
small cell lung carcinoma |
NDP52 |
calcium binding and coiled-coil domain 2 |
NF-kB |
nuclear factor-κB (transcription factor) |
NIC |
niclosamide |
NK |
natural killer cells |
NLRP3 |
NLR family pyrin domain containing 3 inflammasome |
NS4B |
membrane-associated protein involved in viral replication or assembly |
NSPs |
non-structural proteins |
o
|
|
OPTN |
Organ Procurement and Transplantation Network |
ORFs |
Open Reading Frames |
ORF3a |
encodes a viral accessory protein |
ORF8 |
encodes viral accessory protein, Betacoronavirus NS8 protein |
p
|
|
p62 |
SQSTM1(sequestosome 1)- ubiquitin-binding scaffold protein |
PAMPs |
pathogen-associated molecular patterns |
PCD |
programmed cell death |
PEX3 |
peroxisomal Biogenesis Factor |
PI3K |
phosphoinositide 3-kinase, also known as VPS34. |
PI3P |
phosphatidylinositol 3-phosphate |
PINK1 |
PTEN induced kinase 1 |
PKR |
protein kinase R |
PMP |
peroxisome membrane protein |
PP1a |
protein phosphatase 1 |
PRKN |
Parkin RBR E3 ubiquitin protein ligase |
PTEN |
fosfatidilinositol-3,4,5-trisfosfato 3-fosfatasa |
PV |
Poliovirus |
PYCARD |
apoptosis-associated speck-like protein containing a CARD (or ASC) |
PYD |
pyrin domain |
r
|
|
Rab-7a |
Ras-related protein late-endosomal / lysosomal GTPase |
RCD |
regulated cell death |
RHIM |
homotypic interaction motif |
Ribavirin |
antiretroviral medication inhibits- RNA/DNA viruses |
RIP |
proteins containing a receptor-interacting protein |
Ritonavir |
antiretroviral medication, protease inhibitors |
RNP |
ribonucleoprotein complexes |
ROS |
reactive oxygen species |
RTC |
replication and transcription complex |
Ruxolitinib |
Janus kinase inhibitor |
s
|
|
SMVs |
single-membrane vesicles |
SNAP |
soluble N-ethylmaleimidesSensitive factor attachment proteins |
SNAP29 |
synaptosome associated protein 29, SNARE protein, in autophagy |
SNARE |
SNAP receptor |
SNX27 |
sorting nexin family member 27 |
STX17 |
Syntaxin 17, autophagosomal SNARE protein |
t
|
|
TAK1 |
transforming growth factor beta-activated kinase 1 |
Tax1BP1 |
Tax1-binding protein 1 |
TGN |
trans-Golgi network |
TNFR1 |
tumor necrosis factor receptor 1 |
TMEM41B |
transmembrane protein 41B |
TMPRSS2 |
transmembrane serine 2 protease |
Tenofovir DF |
tenofovir disoproxil fumarate, HIV medication |
v
|
|
VAMP8 |
vesicle-associated membrane protein 8 |
Vero E6 |
epithelial cell from African green monkey |
Viroporin |
small hydrophobic multifunctional viral proteins |
VMP1 |
vacuolar membrane protein 1 |
VPS |
vacuolar protein sorting proteins (as VPS26, VPS29 and VPS35) |
Vps34 |
class III phosphoinositide 3-kinase (PI3K) |
VZV |
Varicella zoster virus |
w
|
|
WHO |
World Health Organization |
z
|
|
ZBP1 |
Z-DNA binding protein |