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. 2023 Apr 23;24(9):7734. doi: 10.3390/ijms24097734
a
A549 human lung cells
ACE2 angiotensin-converting enzyme 2
AKT-mTOR signaling protein kinase B-mammalian target of rapamycin complex
APCs antigen presenting cells
Arl8b Arf-like GTPases
ARP2/3 actin-related protein 2/3 complex
ARH-77 B lymphoblast cell line
ASC adaptor apoptosis-associated speck-like protein with a caspase-1 recruitment domain
ATG autophagy-related genes
ATP6AP1 S1 subunit of the enzyme V-type proton ATPase.
b
BCL-xL B-cell lymphoma-extra large
BECN1(Beclin-1) mammalian ortholog of the yeast autophagy-related gene 6
BORC-ARL8b complex multisubunit complex- regulates lysosome positioning
c
Calu-3 human bronchial epithelial cells
CARD caspase recruitment domain
CatB/L cathepsin B and L
CAV Coxsackie viruses
c-Myc proto-oncogene
CNS central nervous system
CXCR-4 C-X-C chemokine receptor type 4
d
3D organoids miniature 3-dimensional structures that can mimic the structure and function of different tissues
DAMPs damage-associated molecular patterns
DENV Dengue virus
DMV double-membrane vesicles
Dolutegravir antiretroviral medication
e
EBV Epstein Bar virus
eIF2a translation elongation factor
Emtricitabine nucleoside reverse-transcriptase inhibitor
ER endoplasmic reticulum
f
FAM134 reticulon protein- ER-phagy receptor
g
GABARAP GABA type receptor-associated protein
GSDMD gasdermin D
GTPase hydrolase enzyme binding nucleotide guanosine triphosphate
h
HCV hepatitis C virus
HEK 293T human embryonic kidney cells
HIF-1 hypoxia-induced transcription factor-1
Hsc70 heat shock cognate 71 kDa protein
HSV herpes simplex virus type I
HOPS homotypic fusion and protein sorting
i
ICP34.5 infected cell protein 34.5
IFN interferon
iPSCs human induced pluripotent stem cells
j
JAK1/2 Janus kinase- (tyrosine kinases)
k
KSHV Kaposi’s sarcoma-associated herpes virus
l
LAMP1 lysosomal associated membrane glycoprotein 1
LAMP2A lysosomal associated membrane protein 2
LC3 microtubule associated protein 1 light chain 3B
LIR LC3-interacting region
Lopinavir antiretroviral protease inhibitor
m
MAVS mitochondrial antiviral-signaling protein
MCL-1 induced myeloid leukemia cell differentiation protein
MHC major histocompatibility complex
MHV murine hepatitis virus
mTORC1/S6K/4EBP1 mammalian target of rapamycin complex 1/p70 ribosomal S6 kinases/4E-binding protein 1
n
NBR1 neighbor of BRCA1 gene
NCI-BL 2171 small cell lung carcinoma
NDP52 calcium binding and coiled-coil domain 2
NF-kB nuclear factor-κB (transcription factor)
NIC niclosamide
NK natural killer cells
NLRP3 NLR family pyrin domain containing 3 inflammasome
NS4B membrane-associated protein involved in viral replication or assembly
NSPs non-structural proteins
o
OPTN Organ Procurement and Transplantation Network
ORFs Open Reading Frames
ORF3a encodes a viral accessory protein
ORF8 encodes viral accessory protein, Betacoronavirus NS8 protein
p
p62 SQSTM1(sequestosome 1)- ubiquitin-binding scaffold protein
PAMPs pathogen-associated molecular patterns
PCD programmed cell death
PEX3 peroxisomal Biogenesis Factor
PI3K phosphoinositide 3-kinase, also known as VPS34.
PI3P phosphatidylinositol 3-phosphate
PINK1 PTEN induced kinase 1
PKR protein kinase R
PMP peroxisome membrane protein
PP1a protein phosphatase 1
PRKN Parkin RBR E3 ubiquitin protein ligase
PTEN fosfatidilinositol-3,4,5-trisfosfato 3-fosfatasa
PV Poliovirus
PYCARD apoptosis-associated speck-like protein containing a CARD (or ASC)
PYD pyrin domain
r
Rab-7a Ras-related protein late-endosomal / lysosomal GTPase
RCD regulated cell death
RHIM homotypic interaction motif
Ribavirin antiretroviral medication inhibits- RNA/DNA viruses
RIP proteins containing a receptor-interacting protein
Ritonavir antiretroviral medication, protease inhibitors
RNP ribonucleoprotein complexes
ROS reactive oxygen species
RTC replication and transcription complex
Ruxolitinib Janus kinase inhibitor
s
SMVs single-membrane vesicles
SNAP soluble N-ethylmaleimidesSensitive factor attachment proteins
SNAP29 synaptosome associated protein 29, SNARE protein, in autophagy
SNARE SNAP receptor
SNX27 sorting nexin family member 27
STX17 Syntaxin 17, autophagosomal SNARE protein
t
TAK1 transforming growth factor beta-activated kinase 1
Tax1BP1 Tax1-binding protein 1
TGN trans-Golgi network
TNFR1 tumor necrosis factor receptor 1
TMEM41B transmembrane protein 41B
TMPRSS2 transmembrane serine 2 protease
Tenofovir DF tenofovir disoproxil fumarate, HIV medication
v
VAMP8 vesicle-associated membrane protein 8
Vero E6 epithelial cell from African green monkey
Viroporin small hydrophobic multifunctional viral proteins
VMP1 vacuolar membrane protein 1
VPS vacuolar protein sorting proteins (as VPS26, VPS29 and VPS35)
Vps34 class III phosphoinositide 3-kinase (PI3K)
VZV Varicella zoster virus
w
WHO World Health Organization
z
ZBP1 Z-DNA binding protein