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COLO357 (CO) vs. MIA PaCa (M).
| Features in CO Compared to M | Associated Features | |
|---|---|---|
| Prognostic factors [59,60,61,62] | Higher osteopontin | Invasiveness |
| Higher BMP2 | Poor survival | |
| Higher CXCR 4 (receptor and protein) | Cell survival, proliferation, migration, invasion, and metastasis. | |
| Predictive factors [63,64] | More sensitive to 5FU, Irinotecan, Cisplatin | |
| Less sensitive to Gem and Oxaliplatin |
