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. 2023 Apr 27;24(9):7962. doi: 10.3390/ijms24097962

Table 3.

Essential oils with appetite-enhancing effects in animal models.

No. Essential Oil Major Compounds Route of Administration Dose Duration Species Mechanism References
1 Lavender essential oil Linalool
1,8-Cineole (Eucalyptol)
Camphor
Inhalation 100,000× dilution in water 15 min/day, 33 days Wistar rats Decrease WAT, BAT, and adrenal SNA; increase gastric PSNA [37]
2 Fennel essential oil trans-Anethole
Fenchone
Mix with diet 100 mg/kg of diet 3 weeks Pietrain × (Landrace × Large White) pigs n/a [39]
3 Zingiber zerumbet essential oil Zerumbone Inhalation 100× dilution in water 5 weeks Sprague Dawley rats Decrease BAT SNA [46]
4 Curry essential oil trans-Anethole
2-Methyl-3-phenylpropanal
Inhalation 4.5 × 10−4 mg/cage 1 h ddY mice n/a [53]
5 Cinnamon essential oil trans-Cinnamaldehyde
trans-2-Methoxycinnamaldehyde
Mix with diet 7% (w/w) of diet 15 days Crossbred bulls n/a [56]
6 Clove essential oil Eugenol
Eugenol acetate
Mix with diet 3.5% (w/w) of diet 15 days Crossbred bulls n/a [56]
7 Amomum villosum Lour. essential oil Bornyl acetate
Camphor
Oral 8, 16, 32 mg/kg 12 days Sprague Dawley rats n/a [58]
8 Nutmeg essential oil Sabinene
α-Pinene
Inhalation 7.4 × 10−7 mg/cm3 1 h ddY mice n/a [65]
9 Cinnamon essential oil trans-Cinnamaldehyde
trans-2-Methoxycinnamaldehyde
Inhalation 4.5 × 10−4~4.5 × 10−3 mg/cage 1 h ddY mice n/a [67]
10 Clove essential oil Eugenol
Eugenol acetate
Inhalation 4.5 × 10−4~4.5 × 10−3 mg/cage 1 h ddY mice n/a [67]
11 Fennel essential oil trans-Anethole
Fenchone
Inhalation 4.5 × 10−4~4.5 × 10−3 mg/cage 1 h ddY mice n/a [67]
12 Cang-ai essential oil Eugenol
1,8-Cineole
Oral 4.6 μg/kg/day 28 days Sprague Dawley rats n/a [74]

BAT, brown adipose tissue; n/a, not applicable; PSNA, parasympathetic nerve activity; SNA, sympathetic nerve activity; WAT, white adipose tissue.