Table 5.

Evaluation of GRADE pro GDT: ⊕◯◯◯ Very low, ⊕⊕◯◯ Low, ⊕⊕⊕◯ Moderate, ⊕⊕⊕⊕ High.

Certainty Assessment							No. of Patients		Effect		Certainty
No. of studies	Study design	Risk of bias	Inconsistency	Indirectness	Imprecision	Other considerations	MRONJ Maxillary	MRONJ Mandibular	Relative (95% CI)	Absolute (95% CI)
14	Observational studies	Not serious	not serious	not serious	not serious	none	55/4201 (1.4%)	88/4243 (2.1%)	OR 0.68 (0.48 to 0.95)	7 fewer per 1.000 (from 11 fewer to 1 fewer)	⨁⨁◯◯ Low