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Radiolabeled 125I-Ang-(1–12) Internalization −/+mAb. Internalization of radiolabeled 125I-Ang-(1–12) in confluent ARPE-19 cells at 37°C for 4 h in the presence and absence of mAb (1 mg/mL). All experiments were performed at least 3 times or more on different passages. Values are expressed in terms of counts per milligram protein (*P < 0.0001 vs. −mAb). Details are in Methods section. ARPE-19, adult retinal pigment epithelial-19.
