Figure 7.
Triton-soluble and triton-insoluble aSyn protein levels were measured in the ventral midbrain of 5–9 (A and C) and 12–19 (B and D) month old mice treated with saline (WT=3–4, 13a2=4) or MnCl (WT=4, 13a2=4). aSyn protein levels were normalized to β-actin and calculated as relative to WT-Saline. Representative blots of aSyn (14kDa) and the loading control β-actin (42 kDa) are shown, WS=WT-saline, WM=WT-MnCl, AS=13a2-saline, and AM=13a2-MnCl treatment. * represents p≤0.05 compared to WT same treatment, Δ represents p≤0.05 compared to 13a2-saline.