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. Author manuscript; available in PMC: 2023 May 12.

Published in final edited form as: Neurotoxicology. 2017 Jun 6;64:256–266. doi: 10.1016/j.neuro.2017.06.005

Table 2.

Sensorimotor analysis in wildtype and Atp13a2 knockout mice at 5–9 months of age

		WT		13a2
		Saline	MnCl₂	Saline	MnCl²
Challenging Beam
	Time	8.94±1.19	8.47±1.25	11.13±1.04	9.32±1.24
	Steps	18.11±0.80	17.28±0.46	17.45±0.36	16.75±0.66
	Errors	3.11±0.70	3.83±0.42	3.98±0.54	3.43±0.35
Spontaneous Activity
	Rears	10.86±1.71	8.38±1.91	9.00±1.66	13.13±3.61
	Forelimb Steps	29.71±5.14	29.38±4.06	29.50±3.49	37.63±7.15
	Hindlimb Steps	18.57±4.48	13.25±1.98	14.75±3.53	17.25±4.30
	Groom Time (s)	18.78±3.86	16.40±6.01	14.44±3.05	19.32±3.54
Gait
	Stride Length	5.59±0.22	6.26±0.21	5.95±0.21	5.41±0.27
	Max Difference	2.03±0.20	2.55±0.30	2.00±0.23	2.58±0.39

Mean ± SEM shown; WT=wildtype, 13a2=Atp13a2 knockout