. 2023 May 7;24(9):8399. doi: 10.3390/ijms24098399

Table 1.

Detailed statistics of the BCR-free survival analysis according to the optimized expression cutpoints. The terms “low” and “high” define the expression level below or above the optimized cutpoint, respectively, and the associated BCR prognosis.

	Cutpoint	n < cp	n > cp	HR (95% CI)	p-Value	rmean (se_rmean)	n₀	n_events	Endtime
AR	560.1	278	219	1.46 (0.917–2.32)	0.109
ESR1	137.3	145	352	1.87 (1.06–3.31)	0.029
Low (fav)						3551.66 (275.68)	122	15	4604
High (unfav)						2295.26 (154.35)	298	57	3524
ESR2	11	246	251	1.45 (0.903–2.33)	0.122
PGR	46.91	61	436	0.466 (0.267–0.813)	0.006
Low (unfav)						1905.99 (286.66)	44	15	3487
High (fav)						3180.63 (203.53)	376	57	4604
NR3C1	528.5	87	410	0.687 (0.406–1.16)	0.16
KLK2	138,600	276	221	0.677 (0.418–1.1)	0.11
KLK3	253,100	123	374	0.423 (0.265–0.677)	0.0002
Low (unfav)						1742.94 (207.64)	104	30	3253
High (fav)						3442.65 (182.64)	316	42	4604
FOLH1	19,080	360	137	1.6 (0.986–2.58)	0.054
Low (fav)						3231.79 (212.73)	308	46	4604
High (unfav)						2210.95 (224.19)	112	26	3524
CDH1	9554	151	346	0.545 (0.342–0.868)	0.009
Low (unfav)						2119.8 (202.9)	118	32	3524
High (fav)						3315.46 (234.69)	302	40	4604
VIM	11,340	407	90	1.85 (1.11–3.07)	0.017
Low (fav)						3298.58 (192.62)	345	51	4604
High (unfav)						1474.64 (120.12)	75	21	2211
CTNNB1	8689	321	176	1.39 (0.863–2.25)	0.172
MMP2	3529	419	78	1.46 (0.834–2.54)	0.184
MMP3	0.4285	91	405	2.93 (1.18–7.27)	0.015
Low (unfav)						3999.75 (302.74)	76	5	4604
High (fav)						2341.89 (134.3)	344	67	3524
MMP9	238.6	294	203	1.43 (0.902–2.28)	0.126
PSA	6.9	224	283	1.93 (1.15–3.25)	0.012
Low (fav)						3500.86 (252.03)	178	20	4604
High (unfav)						2258.85 (155.49)	242	52	3487